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Voriconazole molecule Illustration and Icon
Voriconazole molecule
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A stylized structural diagram displays a triazole antifungal small-molecule drug, showing aromatic rings and heteroatoms colored by element (nitrogen in blue, oxygen in red, fluorine in green, carbon in gray, hydrogen in white). In biological hierarchy, it is a molecule within a therapeutic class used in pharmacotherapy to disrupt fungal physiology. In medicinal chemistry and pharmacology, it inhibits cytochrome P450 14α-demethylase (CYP51), blocking ergosterol biosynthesis at the fungal endoplasmic reticulum and impairing cell membrane formation.
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