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Von willebrand factor multimers plasma vwf Illustration and Icon

Von willebrand factor multimers plasma vwf

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Stylized schematic showing bead-on-a-string polymers representing circulating multimers of the plasma glycoprotein von Willebrand factor (VWF). In biological hierarchy, VWF is a multimeric protein within the hemostatic system of the circulatory system. In hematology and biochemistry, these disulfide-linked multimers vary in size, with higher–molecular-weight forms being most active. Functionally, VWF mediates platelet adhesion to subendothelial collagen and carries/stabilizes coagulation factor VIII (FVIII) at sites of vascular injury in blood plasma.

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