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Vesiculovirus Vsv Spike Pseudotyped Illustration and Icon
Vesiculovirus Vsv Spike Pseudotyped
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Diagram of a bullet-shaped, enveloped virion used for pseudotyping with vesicular stomatitis virus glycoprotein. The viral envelope is studded with VSV-G (vesicular stomatitis virus glycoprotein) spikes that surround a lipid bilayer and matrix (M) protein, enclosing a helical nucleocapsid of nucleoprotein (N) wrapped around a negative-sense single-stranded RNA (ssRNA) genome. In virology and microbiology, this architecture represents the genus Vesiculovirus (family Rhabdoviridae). Pseudotyping with VSV-G broadens cell entry and is commonly applied in viral vector production and gene delivery studies.
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