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vascular-remodeling-4

Vascular remodeling 4 Illustration and Icon

Vascular remodeling 4

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A schematic cross-section of an artery shows concentric vascular remodeling with pronounced wall thickening and narrowed lumen. The image depicts the arterial wall hierarchy: cells (vascular smooth muscle cells, VSMCs) embedded in extracellular matrix (ECM) forming the tunica intima and tunica media, surrounded by the outer adventitia, within the cardiovascular system. In vascular biology, histology, and pathology, this tissue-level remodeling alters vascular resistance and blood pressure by decreasing lumen caliber and increasing arterial stiffness, reflecting proliferative and matrix-deposition changes in the vessel wall.

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