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type-3-secretion-system

Type 3 secretion system Illustration and Icon

Type 3 secretion system

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A cross-sectional schematic depicts a syringe-like bacterial injectisome spanning the cell envelope of a Gram-negative bacterium. This multi-protein secretion apparatus (type: protein complex) extends from the cytoplasmic sorting platform through the inner membrane (IM), peptidoglycan (PG), and outer membrane (OM) to an extracellular needle. In the hierarchy, it is a membrane-embedded nanomachine within a prokaryotic cell. In microbiology and pathogenesis, it translocates effector proteins from the bacterial cytosol into eukaryotic host cells, enabling adherence, immune evasion, and virulence.

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