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Tumor microenvironment Illustration and Icon
Tumor microenvironment
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A schematic of a solid tumor shows densely packed neoplastic cells (blue) surrounded by fibroblast-like stromal cells (green) and irregular, branching blood vessels (red). At a hierarchical level, individual malignant cells reside within tumor tissue embedded in stroma. In oncology and pathology, this microenvironment supports angiogenesis and nutrient exchange that enable proliferation and invasion. The entities depicted are cells and vascular structures in tissue. Abbreviation: ECM (extracellular matrix) denotes the supporting stromal scaffold.
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