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Tuft cell Illustration and Icon
Tuft cell
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A stylized depiction of a chemosensory epithelial cell with an apical tuft of microvilli and a central, ovoid nucleus. In biological hierarchy, it represents a specialized cell within mucosal epithelium, studied in histology, physiology, and immunology. This cell detects luminal chemicals and contributes to type 2 immune signaling by releasing IL-25 (interleukin-25) and acetylcholine, which activate ILC2 (group 2 innate lymphoid cells) and modulate epithelial secretion and barrier function.
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