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Translocation reciprocal Illustration and Icon
Translocation reciprocal
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Schematic illustrating a chromosomal reciprocal translocation: two nonhomologous, banded metaphase chromosomes exchange distal segments at matched breakpoints (dashed lines), producing two derivative chromosomes. An arrow denotes the exchange event. In cytogenetics and molecular genetics, this structural rearrangement occurs within the cell nucleus and can alter gene linkage and expression without changing overall DNA content. The image emphasizes chromosome-level hierarchy within the genome and depicts the karyotypic mechanism relevant to karyotype analysis and genetic counseling.
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