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Transition squamous epithelial cells columnar epithelial cells Illustration and Icon

Transition squamous epithelial cells columnar epithelial cells

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A histologic diagram illustrates a squamocolumnar junction (SCJ), where multilayered stratified squamous epithelium transitions to simple columnar epithelium along a mucosal surface. The hierarchy shows epithelial cells composing an epithelium that constitutes part of the mucosa. In histology and anatomy, stratified squamous cells provide mechanical protection, whereas columnar cells mediate secretion and absorption. This junctional zone is a key site in pathology for assessing metaplasia and dysplasia within mucosa-lined hollow organs.

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