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Toxin clostridium difficile 2 Illustration and Icon
Toxin clostridium difficile 2
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A stylized schematic depicts a multi-domain bacterial exotoxin produced by Clostridioides difficile (C. difficile). In biological hierarchy, it is a virulence protein made by a Gram-positive bacterium that acts on epithelial cells within colonic mucosa. In microbiology and pathology, the principal toxins TcdA (toxin A) and TcdB (toxin B) glucosylate Rho-family GTPases, disrupting the actin cytoskeleton and tight junctions, which promotes inflammation, diarrhea, and colitis. The entity illustrated is a protein molecule that operates extracellularly before binding to target cells.
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