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Toll like receptor Illustration and Icon
Toll like receptor
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A stylized schematic depicting a dimeric Toll-like receptor (TLR), a membrane-bound pattern-recognition receptor (PRR) of the innate immune system. The illustration abstracts two juxtaposed receptor subunits with putative cytosolic signaling domains, representing a protein complex at the cell surface or endosomal membrane. In immunology and cell biology, TLRs detect pathogen-associated molecular patterns (PAMPs) and initiate signaling to activate NF-kappa B and interferon pathways, promoting inflammation and antimicrobial defense. Hierarchically, it shows a transmembrane protein within a cell participating in host-defense signaling.
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