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Tenofovir alafenamide Illustration and Icon
Tenofovir alafenamide
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Tenofovir alafenamide. The illustration presents a ball-and-stick chemical structure highlighting carbon, oxygen, nitrogen, phosphorus, and sulfur atoms with ester, amide, and phosphoramidate linkages. In medicinal chemistry and pharmacology, this small-molecule prodrug (TAF) belongs to the antiretroviral nucleotide analogue class. At the cellular level, it is converted intracellularly to tenofovir diphosphate, a nucleos(t)ide reverse transcriptase inhibitor (NRTI) that suppresses HIV-1 and hepatitis B virus replication by inhibiting viral DNA synthesis.
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