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Synapse high density dopamine receptor 2 Illustration and Icon
Synapse high density dopamine receptor 2
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An illustrative diagram of a chemical synapse depicts a presynaptic axon terminal releasing dopamine-containing vesicles into the synaptic cleft toward a postsynaptic membrane densely populated with dopamine D2 receptors (D2R). The D2R is a G protein–coupled receptor (GPCR) embedded in the neuronal plasma membrane, shown here as a receptor protein within a neuron of the nervous system. In neuroanatomy and neurophysiology, these receptors mediate dopaminergic signaling that modulates neuronal excitability and synaptic transmission.
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