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Stim1 Protein Illustration and Icon
Stim1 Protein
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A schematic depicts stromal interaction molecule 1 (STIM1), a dimeric membrane protein with paired transmembrane helices (light blue) and extended cytosolic coiled-coil regions (purple). In cell biology and biochemistry, this protein resides in the endoplasmic reticulum membrane of eukaryotic cells and functions as a Ca2+ sensor. Upon store depletion, it initiates store-operated calcium entry (SOCE) by activating ORAI channels at the plasma membrane. The figure represents a protein within an organelle of a cell; species is unspecified.
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