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Secreted protein acidic rich cysteine sparc osteonectin Illustration and Icon
Secreted protein acidic rich cysteine sparc osteonectin
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A ribbon diagram depicts the matricellular protein SPARC (secreted protein acidic and rich in cysteine), also known as osteonectin, with alpha-helices and beta-strands connected by flexible loops. In biological hierarchy, it is a protein molecule situated in the extracellular matrix of connective tissues. In biochemistry and structural biology, SPARC binds collagen and Ca2+ (calcium ion), modulating cell–matrix interactions and bone mineralization. Its site of action is extracellular, where it influences matrix assembly and tissue remodeling.
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