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Rat cecal ligation puncture 2 Illustration and Icon
Rat cecal ligation puncture 2
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A ventral view of a laboratory rat (Rattus norvegicus) with the abdominal wall opened to expose the gastrointestinal tract, illustrating the cecal ligation and puncture (CLP) procedure. The cecum, an organ of the large intestine within the digestive system, is targeted with a needle to produce fecal leakage and polymicrobial peritonitis, creating an in vivo model of sepsis. This surgical technique is used in anatomy, physiology, pathology, and microbiology research to study systemic inflammatory responses and organ dysfunction in mammals.
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