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Randall selitto test rat Illustration and Icon
Randall selitto test rat
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A gloved researcher restrains a white laboratory rat while a mechanical analgesy-meter with a digital readout applies pressure via a clamp to the animal’s paw. This setup depicts the Randall–Selitto nociception assay used in physiology and pharmacology to quantify mechanical pain threshold and assess analgesic efficacy or hyperalgesia. The organism is Rattus norvegicus (rat), serving as an animal model. In biological hierarchy, cutaneous nociceptors in the paw (PNS, peripheral nervous system) transduce stimuli for processing by the CNS (central nervous system).
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