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Protein polyubiquitin chain Illustration and Icon
Protein polyubiquitin chain
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A schematic depicts a polyubiquitin chain (linked Ub units) conjugated to a substrate polypeptide. In cellular hierarchy, Ub (ubiquitin) is a small protein acting as a post-translational modifier within the UPS (ubiquitin–proteasome system) of eukaryotic cells. The modification tags the target protein for recognition by the 26S proteasome, regulating turnover, trafficking, and signaling. The structure shown is a molecular complex located in the cytosol and nucleus. Field: biochemistry, molecular biology, and cell biology.
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