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Protein hydrophobic pocket Illustration and Icon
Protein hydrophobic pocket
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A stylized depiction of a globular protein with an internal nonpolar binding cavity highlighted in red. The illustration shows a submolecular pocket nested within a folded polypeptide macromolecule, reflecting the hierarchy of a binding site within a protein. In structural biology and biochemistry, such cavities accommodate hydrophobic ligands, drive molecular recognition, and influence catalytic specificity. The site is located in the protein interior, enclosed by apolar side chains, and is a common target for structure-based ligand design.
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