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Protein a mnase Illustration and Icon
Protein a mnase
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A stylized schematic representing Protein A–MNase (micrococcal nuclease, MNase) fusion protein used in chromatin profiling. In the biological hierarchy, this recombinant protein targets antibody-bound chromatin within the cell nucleus of eukaryotic cells. In biochemistry and molecular epigenetics, it serves as an antibody-tethered endonuclease enabling CUT&RUN (Cleavage Under Targets and Release Using Nuclease) to selectively cleave and release DNA at protein–DNA interaction sites. The entity illustrated is a protein reagent acting at the chromatin level inside nuclei; no species or human demographic features are specified.
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