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Prostate organoid Illustration and Icon
Prostate organoid
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A schematic shows a hollow spheroid of epithelial cells arranged as a single layer around a central lumen, representing an in vitro three-dimensional (3D) model of the prostate gland. In the biological hierarchy, individual epithelial cells assemble into glandular tissue that mimics a prostatic acinus within the male reproductive system. Pertinent to cell biology, developmental biology, and urology, this organoid type is used to investigate epithelial differentiation, androgen-responsive secretion, carcinogenesis, and to screen pharmacologic agents that affect prostate function.
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