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Prion protein structure Illustration and Icon
Prion protein structure
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A ribbon diagram illustrates the fold of the prion protein (PrP), with gray alpha-helices and colored arrows denoting antiparallel beta-strands connected by loops. Within the biological hierarchy, secondary-structure elements assemble into a single polypeptide chain constituting a protein macromolecule. In structural biology, biochemistry, and pathology, this conformational architecture underlies normal protein function and, when misfolded, enables templated aggregation characteristic of prion diseases.
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