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Primary follicle Illustration and Icon
Primary follicle
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Histological schematic depicting an ovarian primary follicle with a central primary oocyte surrounded by a developing zona pellucida (ZP) and one to several layers of cuboidal granulosa cells. Hierarchically, the oocyte (cell) resides within a follicle (tissue-level anatomical structure) located in the ovarian cortex of the female reproductive system. In histology and reproductive physiology, this pre-antral stage supports early oocyte growth and folliculogenesis without an antral cavity, preparing the unit for subsequent endocrine activity and potential ovulation.
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