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Pip2 molecule simple Illustration and Icon
Pip2 molecule simple
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A simplified schematic of phosphatidylinositol 4,5‑bisphosphate (PIP2), depicting a diacylglycerol lipid with two hydrophobic fatty‑acyl tails and a polar inositol head group bearing phosphate moieties; the head is labeled IP3 to indicate the product inositol 1,4,5‑trisphosphate (IP3) generated upon phospholipase C (PLC) cleavage, with diacylglycerol (DAG) remaining in the membrane. In cell biology and biochemistry, this membrane phospholipid resides on the inner leaflet of the plasma membrane of eukaryotic cells, acting as a precursor for second‑messenger signaling that regulates cytosolic Ca2+ release.
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