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Pip2 molecule Illustration and Icon
Pip2 molecule
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Ball-and-stick molecular diagram depicting phosphatidylinositol 4,5-bisphosphate (PIP2), a glycerophospholipid with an inositol ring headgroup bearing two phosphate groups and a diacylglycerol backbone with two long fatty acyl chains. In biological hierarchy, it is a signaling lipid embedded in the inner leaflet of the plasma membrane of eukaryotic cells. In cell biology and biochemistry, PIP2 serves as a substrate for phospholipase C (PLC), producing diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) to modulate ion channels and cytoskeletal dynamics.
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