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Petri Dish Mla Hprt Genotoxicity Test Illustration and Icon
Petri Dish Mla Hprt Genotoxicity Test
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Top view of a petri dish with blue culture medium containing multiple orange–brown mammalian cell colonies. The schematic represents endpoint plating for mammalian gene mutation tests such as the Mouse Lymphoma Assay at the TK locus and the HPRT/XPRT mutation assay after selective growth (e.g., 6‑thioguanine or trifluorothymidine) in soft/semisolid agar. Used to quantify mutant frequency for in vitro genotoxicity and mutagenicity assessment consistent with OECD TG 476 and TG 490.
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