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Paw edema test mice Illustration and Icon
Paw edema test mice
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A gloved researcher restrains a white laboratory mouse (Mus musculus) by the scruff while its hind limb is positioned above a fluid-filled chamber of a volume-displacement plethysmometer. This in vivo assay, used in pharmacology and physiology, quantifies inflammation by measuring hind paw volume, a tissue-level endpoint within the musculoskeletal system of the organism. The setup supports screening of anti-inflammatory drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs), by detecting induced edema in the mouse paw.
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