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P53 protein Illustration and Icon
P53 protein
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A molecular illustration shows a transcription factor bound to a DNA double helix, depicting p53 (TP53, tumor protein p53) as a surface-rendered protein engaging sequence-specific sites in chromosomal DNA. Within the biological hierarchy, this macromolecule is a nuclear protein operating within the genome to modulate transcription. In molecular biology and oncology, p53 functions as a tumor suppressor that coordinates cell-cycle arrest, apoptosis, and DNA repair. The image represents a protein–DNA complex located in the cell nucleus.
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