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osteoclast

cell osteoclast Illustration and Icon

cell osteoclast

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Illustration of a multinucleated osteoclast, a large bone-resorbing cell with multiple nuclei and a ruffled cell border. In biological hierarchy, it is a specialized cell within bone tissue of the skeletal system. In histology and physiology, osteoclasts degrade mineralized matrix at the bone surface (Howship’s lacuna) by secreting hydrogen ions (H+) and proteolytic enzymes from lysosomes. The depiction highlights several nuclei and abundant intracellular organelles consistent with high metabolic activity.

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