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nmda-receptor

Nmda receptor Illustration and Icon

Nmda receptor

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A stylized schematic of the NMDAR (N-methyl-D-aspartate receptor), an ionotropic glutamate receptor depicted as a tetrameric ligand-gated cation channel spanning the postsynaptic plasma membrane of a neuron. In neuroanatomy and neurophysiology, this transmembrane protein complex mediates synaptic transmission and plasticity by permitting Ca2+ and Na+ influx and K+ efflux when activated by glutamate and glycine and relieved of Mg2+ block. Within the biological hierarchy, it represents a membrane protein within the synapse of the central nervous system.

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