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Nlrp3 Illustration and Icon
Nlrp3
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A stylized schematic depicts the NOD‑like receptor family pyrin domain‑containing 3 (NLRP3) inflammasome as stacked domains linking a sensor to adaptor and effector proteins. The sensor protein NLRP3 (a cytosolic pattern‑recognition receptor) recruits ASC (apoptosis‑associated speck‑like protein containing a CARD) which in turn engages CASP1 (caspase‑1), forming a supramolecular complex. In the biological hierarchy, individual proteins assemble within the cytosol of innate immune cells to regulate inflammatory signaling, enabling cytokine maturation and pyroptosis. This illustration pertains to immunology and cell biology.
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