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Neuron neurofibrillary tangles Illustration and Icon
Neuron neurofibrillary tangles
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A schematic neuron shows a triangular soma with a nucleus, branched dendrites, and a long axon, with wavy intracytoplasmic filaments representing neurofibrillary tangles (NFTs). This cell-level depiction belongs to neuroanatomy and neuropathology, illustrating aggregates of hyperphosphorylated tau (microtubule-associated protein tau, MAPT) within central nervous system tissue. Such pathology disrupts microtubules, impairs axonal transport, and undermines synaptic signaling performed by this excitable nerve cell.
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