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na-v-1-8-tet-tox-construct

Na v 1 8 tet tox construct Illustration and Icon

Na v 1 8 tet tox construct

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A schematic depicts a Nav1.8 (SCN10A)–expressing peripheral sensory neuron from the skin projecting through the dorsal root ganglion (DRG) to synapse in the dorsal horn of the spinal cord, alongside a motor efferent for reflex context. In neuroanatomy and neurophysiology, this cell is part of the somatosensory pathway within the peripheral nervous system. A tetanus toxin light chain (TeTxLC) construct is indicated to silence synaptic transmission, enabling functional analysis of afferent signaling in Homo sapiens (human). The illustrated entities are neurons (cells) within the nervous system.

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