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muscle-actin

Muscle actin Illustration and Icon

Muscle actin

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Stylized diagram of the thin filament in striated muscle, showing a double-helical filamentous actin (F-actin) polymer built from globular actin (G-actin) subunits (green), with tropomyosin (Tm; pink strand) lying along the filament and periodic troponin (Tn) complexes (pink ovals). In biological hierarchy, this protein assembly forms part of the sarcomere within a myofibril of muscle tissue. In cell biology, physiology, and biochemistry, the thin filament enables regulated myosin binding and force generation through Ca2+-dependent Tn–Tm control of actin’s regulatory sites.

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