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Mucin gel assembly Illustration and Icon
Mucin gel assembly
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A schematic shows mucin polymerization forming a viscoelastic mucus gel. Linear mucin glycoprotein chains crosslink via terminal S–S (disulfide) bonds, with dense O-linked glycans projecting laterally, creating a hydrated extracellular network above epithelial tissue. In biochemistry and mucosal physiology, this macromolecular assembly constitutes a protective barrier that traps pathogens, lubricates surfaces, and regulates diffusion along respiratory and gastrointestinal mucosa.
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