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Mouse cecal ligation puncture Illustration and Icon
Mouse cecal ligation puncture
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An anesthetized laboratory mouse (Mus musculus) lies supine with a midline laparotomy exposing abdominal organs while a hypodermic needle punctures the cecum after ligation to induce sepsis. In the biological hierarchy, the cecum is an organ segment of the large intestine within the gastrointestinal tract located in the lower abdomen. The scene illustrates the CLP (cecal ligation and puncture) procedure, a surgical technique used in experimental pathology, microbiology, and physiology to produce polymicrobial peritonitis and a systemic inflammatory response for sepsis research.
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