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Monocyte migrating into intima Illustration and Icon
Monocyte migrating into intima
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Illustration of a monocyte, a circulating leukocyte, undergoing transendothelial migration (TEM) through the endothelial cell layer into the tunica intima of a blood vessel. The blue cytoplasm encloses a kidney-shaped, purple nucleus, highlighting cell morphology during diapedesis. In the biological hierarchy, a single immune cell moves across vascular tissue (endothelium within the vessel wall). Relevant fields include immunology, vascular biology, and pathology. Functionally, this trafficking enables tissue surveillance and initiation of inflammatory responses, where monocytes can differentiate into macrophages and dendritic cells within the intimal compartment.
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