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Mitochondrial bax bak channels Illustration and Icon
Mitochondrial bax bak channels
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A simplified diagram of a mitochondrion shows BAX/BAK oligomeric channels in the mitochondrial outer membrane permitting diffusion of small proteins (orange dots) from the intermembrane space. In cell biology and biochemistry, BAX (Bcl-2-associated X protein) and BAK (Bcl-2 homologous antagonist/killer) mediate mitochondrial outer membrane permeabilization (MOMP) during apoptosis. The organelle is depicted with inner membrane cristae, illustrating channel-forming proteins within an organelle inside a eukaryotic cell.
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