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Mitochondria damaged Illustration and Icon
Mitochondria damaged
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A stylized cross-sectional diagram of a damaged mitochondrion, showing an outer mitochondrial membrane (OMM) and a distorted inner mitochondrial membrane (IMM) with swollen cristae surrounding the matrix. In cellular biology and pathology, this organelle resides in the cytoplasm of eukaryotic cells and functions in oxidative phosphorylation to synthesize ATP (adenosine triphosphate). Membrane disruption implies impaired electron transport and increased ROS (reactive oxygen species) generation, compromising energy metabolism and apoptosis signaling within the cell.
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