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Metyrapone Illustration and Icon
Metyrapone
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A 2D skeletal formula depicts a small-molecule ketone consisting of two pyridine rings (nitrogen atoms colored blue) linked by a tertiary carbonyl group (oxygen in red). In biochemical and pharmacology contexts, this compound functions as an inhibitor of CYP11B1 (11β-hydroxylase), reducing glucocorticoid synthesis in the adrenal cortex (zona fasciculata) of the endocrine system. The molecule is used to assess HPA (hypothalamic–pituitary–adrenal) axis function and to manage hypercortisolemia.
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