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Metabotropic receptor 1 Illustration and Icon
Metabotropic receptor 1
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A simplified schematic depicts a metabotropic G protein-coupled receptor (GPCR) with seven transmembrane alpha-helices linked by extracellular and cytoplasmic loops. This membrane protein resides in the plasma membrane of eukaryotic cells, where it couples to heterotrimeric G proteins to initiate second-messenger signaling. In cell biology and neurophysiology, such receptors modulate synaptic transmission and metabolic pathways by transducing extracellular ligand binding into intracellular responses.
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