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Merkel cell polyomavirus Illustration and Icon
Merkel cell polyomavirus
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A schematic cross-section of a non-enveloped, icosahedral virion from the Polyomaviridae family shows an outer capsid with repeating pentameric capsomers and an internal circular double-stranded DNA (dsDNA) genome. The agent depicted is Merkel cell polyomavirus (MCV; also called Human polyomavirus 5), a virus studied in microbiology and pathology for its role in oncogenesis. The genome forms a minichromosome bound to host histones within the particle. This pathogen infects human skin, where it is implicated in Merkel cell carcinoma.
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