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Melanoma asymmetrical Illustration and Icon
Melanoma asymmetrical
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A simplified dermatologic illustration shows an asymmetric, dark brown pigmented macule with an irregular, poorly circumscribed border, representing cutaneous malignant melanoma. Within the biological hierarchy, neoplastic melanocytes (cells) proliferate in the epidermis and may invade the dermis of the skin (organ) in the integumentary system. In dermatology, oncology, and pathology, this lesion exemplifies ABCDE (Asymmetry, Border irregularity, Color variation, Diameter, Evolution) criteria used for melanoma screening. Melanocytes produce melanin, and malignant transformation enables uncontrolled growth with potential for local invasion and metastasis at the skin site.
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