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Medial calcification Illustration and Icon
Medial calcification
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A schematic cross-section of an artery shows calcific deposits within the tunica media encircling a central lumen. The image illustrates vascular anatomy and pathology, depicting the hierarchical layers: intima, media rich in VSMCs (vascular smooth muscle cells) with focal calcium phosphate (hydroxyapatite) deposition, and the outer adventitia. This tissue-level lesion of the arterial wall within the circulatory system increases arterial stiffness and reduces compliance without prominent intimal atheroma, representing a pathologic change rather than a typical lipid-laden plaque.
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