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Maternal separation model superior Illustration and Icon

Maternal separation model superior

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A schematic shows a solitary neonatal rodent resting in a circular container with white nesting material, illustrating the maternal separation (MS) model used in behavioral neuroscience. The entity is an organism (newborn pup) within a controlled laboratory setting, representing an animal model within developmental physiology and neurobiology. This paradigm applies early-life stress to examine hypothalamic–pituitary–adrenal (HPA) axis function, stress hormone secretion, and later behavioral phenotypes. Anatomically, the pup is hairless and altricial, situated alone away from the dam and littermates.

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