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Liver sinusoid Illustration and Icon
Liver sinusoid
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Cross-sectional histology diagram of a hepatic sinusoidal capillary within the liver lobule, showing fenestrated liver sinusoidal endothelial cells (LSEC) lining a blood-filled lumen, with Kupffer cells (KC; liver-resident macrophages) adherent to the endothelium and hepatic stellate cells (HSC; Ito cells) in the perisinusoidal space (space of Disse). Hepatocytes form the surrounding parenchyma. In anatomy and physiology, this microvascular tissue enables exchange of solutes and plasma between blood and hepatocytes and provides immune surveillance and vitamin A storage.
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