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Lipid drug conjugates 1 Illustration and Icon
Lipid drug conjugates 1
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A schematic illustration depicts an amphiphilic molecule comprising a polar lipid head group (white circle), two hydrophobic acyl chains (blue), and a covalently linked drug payload (orange star). In pharmaceutical chemistry and biochemistry, such lipid–drug conjugates (LDCs) act as prodrugs that leverage lipid membrane affinity to improve solubility, absorption, and intracellular delivery. At the hierarchy level, this small molecule can integrate into a biological membrane or assemble within nanocarriers such as liposomes or micelles to enable controlled drug release.
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