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Leptin structure Illustration and Icon
Leptin structure
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A ribbon diagram highlighting the tertiary structure of the hormone leptin (LEP), a secreted protein forming a four-helix bundle typical of class I cytokines. In the biological hierarchy, this molecule is produced by adipocytes within white adipose tissue and acts systemically in the endocrine system on the hypothalamus via the leptin receptor (LEPR). In biochemistry, structural biology, and endocrinology, leptin mediates appetite suppression and energy homeostasis by signaling nutritional status.
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