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late-endosome

Late endosome Illustration and Icon

Late endosome

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A stylized depiction of a membrane-bound vesicle containing multiple internal vesicles, representing a multivesicular body (MVB) in the endocytic pathway. In the biological hierarchy, it is an organelle within the cytoplasm of a eukaryotic cell, part of the endomembrane system that progresses toward lysosomes. In cell biology and physiology, this compartment sorts ubiquitinated membrane proteins into intraluminal vesicles (ILVs) for degradation, mediating receptor downregulation and membrane lipid trafficking.

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