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Lariat Illustration and Icon
Lariat
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A simple schematic shows a lariat topology—a loop with a trailing strand—representing an RNA lariat intermediate formed during pre‑mRNA (precursor messenger RNA) splicing. In molecular biology and biochemistry, this nucleic acid molecule (RNA, ribonucleic acid) arises within the nucleus of eukaryotic cells as part of the spliceosome, enabling intron excision and exon ligation to generate mature mRNA (messenger RNA). Hierarchically, it is a molecule functioning within the nuclear RNA‑processing machinery of the cell.
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